硕士生导师

当前位置: 学院首页 > 师资队伍 > 硕士生导师 > 正文

范红结

发布时间:2023-09-05   作者:董轩   点击数:

姓名:范红结

性别:男

毕业院校:南京农业大学

最高学位:博士

办公电话:

邮箱:fanhj@ahstu.edu.cn

研究方向:兽医微生物致病机制及免疫,猪用新型疫苗创制

一、 个人简历

1968年7月出生,籍贯安徽望江,博士,南京农业大学“钟山学者计划”首席教授,“预防兽医学”学科点长。兼任农业农村部第三届全国动物防疫专家委员会委员,农业农村部第七届新兽药评审专家,教育部高等学校动物医学类专业教学指导委员会委员,中国微生物学会理事,中国畜牧兽医学会兽医公共卫生学分会副理事长等。曾任动物医学院院长、院党委书记等。1996年6月扬州大学传染病与预防兽医学专业硕士研究生毕业后一直在南京农大工作,主持国家和部省级等研究课题30余项,涉及猪链球菌病、猪回肠炎致病机理及免疫预防等方面的研究。在Nature Communications、PNAS、PLoS Pathogens、《畜牧兽医学报》等期刊发表学术论文200余篇。作为主要完成人获国家科技进步奖二等奖、国家教学成果奖二等奖各一项,已培养博士、硕士研究生160余名。入选教育部新世纪人才、江苏特聘教授、全国农业科研杰出人才及创新团队等人才计划。

二、近年主持科研项目:

1、畜禽胞外病原菌免疫逃逸机制,国家重点研发计划课题(2021YFD1800404),2021.09-2025.12,950万元,主持;

2、施马伦贝格传入及跨区域传播模型研究,国家重点研发计划项目子课题(2021YFD1800505-4),2021.05-2025.12,120万元,主持;

3、猪细菌性传染病新型疫苗创制造,普莱柯公司、金宇集团委托项目,2021.05-2027.05,2000万元,主持

4、猪链球菌2型CSP蛋白抑制猪中性粒细胞胞外诱捕网形成的分子机制,国家自然科学基金面上项目(31872480),2019.01-2022.12,60万元,主持;

三、近年部分代表性论著:

1.Jinsheng Tang, Mengru Guo, Min Chen, Bin Xu, Tingting Ran, Weiwu Wang, Zhe Ma, Huixing Lin, Hongjie Fan*. A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis. Nature Communications, 2023, 14:2480.

2.Fei Pan, Mingli Zhu, Ying Liang, Chen Yuan, Yu Zhang, Yuchang Wang, Hongjie Fan, Matthew K. Waldor, ZheMa*. Membrane vesicle delivery of a streptococcal M protein disruptsthe blood-brain barrier by inducing autophagic endothelialcell death. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2023, 120(24):e2219435120.

3.Kai Niu, Yu Meng, Mingxing Liu, Zhe Ma, Huixing Lin, Hong Zhou, Hongjie Fan*. Phosphorylation of GntR reduces Streptococcus suis oxidative stress resistance and virulence by inhibiting NADH oxidase transcription, PLoS Pathogens, 2023, 19(3): e1011227.

4.陈敏,刘明星,张鹏云,蔺辉星,范红结*.副猪格拉瑟菌5型细胞致死性膨胀毒素CdtB破坏猪呼吸道上皮屏障的机制[J].畜牧兽医学报, 2023, 54(1):304-316.

5. Yu Meng, Qing Wang, Zhe Ma, Weiyi Li, Kai Niu, Ting Zhu, Huixing Lin, Chengping Lu, Hongjie Fan*. Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin. PLoS Pathogens, 2022, 18(8):e1010765.

6. Mingxing Liu, Qing Wang, Wenda Wu, Min Chen, Pengyun Zhang, Mengru Guo, Huixing Lin, Zhe Ma, Hong Zhou, Hongjie Fan*. Glaesserella parasuis serotype 5 breaches the porcine respiratory epithelial barrier by inducing autophagy and blocking the cell membrane Claudin-1 replenishment. PLoS Pathogens, 2022, 18(10): e1010912.

7. Ning Xiao, Jiannan Li, Minxue Li, Hong Zhou, Huixing Lin, Hongjie Fan*.

Isolation and In Vitro cultivation of Lawsonia intracellularis from China. Veterinary Microbiology, 2022, 270:109457.

8. Qing Wang, Xiaojing Chang, Mingxing Liu, Qi Lu, Meng Zhu, Huixing Lin, Hongjie Fan*. Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation. Veterinary Research, 2021, 52:135.

9. Minxue Li, Ning Xiao, Jiannan Li, Huixing Lin, Hongjie Fan*. Evaluation of immune efficacy of Omp2 protein against Lawsonia intracellularis in mice. Veterinary Microbiology, 2021,263:109274.

10. Qing Wang, Hong Zhou, Huixing Lin, Zhe Ma, Hongjie Fan*. Porcine circovirus type 2 exploits JNK-mediated disruption of tight junctions to facilitate Streptococcus suis translocation across the tracheal epithelium. VeterinaryResearch, 2020, 51(1):31.

下一篇:岳隆耀